Moholdt T, Hawley JA. Maternal lifestyle interventions: targeting preconception health. Trends Endocrinol Metab. 2020;31:561–9.
Article CAS PubMed Google Scholar
Bulik CM, Hardaway JA. Turning the tide on obesity? Science. 2023;381:463.
Mahajan A, Taliun D, Thurner M, Robertson NR, Torres JM, Rayner NW, et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet. 2018;50:1505–13.
Article CAS PubMed PubMed Central Google Scholar
Driscoll AK, Gregory ECW. Increases in Prepregnancy Obesity: United States, 2016–2019. NCHS Data Brief. 2020;392:1–8.
Langley-Evans SC. Early life programming of health and disease: the long-term consequences of obesity in pregnancy. J Hum Nutr Diet. 2022;35:816–32.
Article PubMed PubMed Central Google Scholar
Leddy MA, Power ML, Schulkin J. The impact of maternal obesity on maternal and fetal health. Rev Obstet Gynecol. 2008;1:170–8.
PubMed PubMed Central Google Scholar
Segovia SA, Vickers MH, Gray C, Reynolds CM. Maternal obesity, inflammation, and developmental programming. Biomed Res Int. 2014;2014:418975.
Article PubMed PubMed Central Google Scholar
Bucher M, Montaniel KRC, Myatt L, Weintraub S, Tavori H, Maloyan A. Dyslipidemia, insulin resistance, and impairment of placental metabolism in the offspring of obese mothers. J Dev Orig Health Dis. 2021;12:738–47.
Article CAS PubMed Google Scholar
Hu Z, Han L, Liu J, Fowke JH, Han JC, Kakhniashvili D, et al. Prenatal metabolomic profiles mediate the effect of maternal obesity on early childhood growth trajectories and obesity risk: the CANDLE study. Am J Clin Nutr. 2022;116:1343–53.
Article CAS PubMed PubMed Central Google Scholar
Basu S, Haghiac M, Surace P, Challier JC, Guerre-Millo M, Singh K, et al. Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation. Obes (Silver Spring). 2011;19:476–82.
Muralimanoharan S, Guo C, Myatt L, Maloyan A. Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity. Int J Obes (Lond). 2015;39:1274–81.
Article CAS PubMed Google Scholar
Suk D, Kwak T, Khawar N, Vanhorn S, Salafia CM, Gudavalli MB, et al. Increasing maternal body mass index during pregnancy increases neonatal intensive care unit admission in near and full-term infants. J Matern Fetal Neonatal Med. 2016;29:3249–53.
Griffiths PS, Walton C, Samsell L, Perez MK, Piedimonte G. Maternal high-fat hypercaloric diet during pregnancy results in persistent metabolic and respiratory abnormalities in offspring. Pediatr Res. 2016;79:278–86.
Dumas O, Varraso R, Gillman MW, Field AE, Camargo CA Jr. Longitudinal study of maternal body mass index, gestational weight gain, and offspring asthma. Allergy. 2016;71:1295–304.
Article CAS PubMed Google Scholar
Guerra S, Sartini C, Mendez M, Morales E, Guxens M, Basterrechea M, et al. Maternal prepregnancy obesity is an independent risk factor for frequent wheezing in infants by age 14 months. Paediatr Perinat Epidemiol. 2013;27:100–8.
Morgan AR, Thompson JM, Murphy R, Black PN, Lam WJ, Ferguson LR, et al. Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study. BMC Med Genet. 2010;11:125.
Article PubMed PubMed Central Google Scholar
Eriksson JG, Sandboge S, Salonen MK, Kajantie E, Osmond C. Long-term consequences of maternal overweight in pregnancy on offspring later health: findings from the Helsinki Birth Cohort Study. Ann Med. 2014;46:434–8.
Lucas D. Structural organization of the bone marrow and its role in hematopoiesis. Curr Opin Hematol. 2021;28:36–42.
Article CAS PubMed PubMed Central Google Scholar
Benova A, Tencerova M. Obesity-Induced Changes in Bone Marrow Homeostasis. Front Endocrinol. 2020;11:294.
Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, et al. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity. Cell Metab. 2014;19:821–35.
Article CAS PubMed PubMed Central Google Scholar
Singer K, DelProposto J, Morris DL, Zamarron B, Mergian T, Maley N, et al. Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells. Mol Metab. 2014;3:664–75.
Article CAS PubMed PubMed Central Google Scholar
Hoyer FF, Zhang X, Coppin E, Vasamsetti SB, Modugu G, Schloss MJ, et al. Bone marrow endothelial cells regulate myelopoiesis in diabetes mellitus. Circulation. 2020;142:244–58.
Article CAS PubMed PubMed Central Google Scholar
Mulder WJM, Ochando J, Joosten LAB, Fayad ZA, Netea MG. Therapeutic targeting of trained immunity. Nat Rev Drug Discov. 2019;18:553–66.
Article CAS PubMed PubMed Central Google Scholar
Netea MG, Joosten LA, Latz E, Mills KH, Natoli G, Stunnenberg HG, et al. Trained immunity: a program of innate immune memory in health and disease. Science. 2016;352:aaf1098.
Article PubMed PubMed Central Google Scholar
Calco GN, Alharithi YJ, Williams KR, Jacoby DB, Fryer AD, Maloyan A, et al. Maternal high-fat diet increases airway sensory innervation and reflex bronchoconstriction in adult offspring. Am J Physiol Lung Cell Mol Physiol. 2023;325:L66–l73.
Article CAS PubMed Google Scholar
Montaniel KRC, Bucher M, Phillips EA, Li C, Sullivan EL, Kievit P, et al. Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers. J Dev Orig Health Dis. 2022;13:727–40.
Article CAS PubMed PubMed Central Google Scholar
Liu X, Quan N. Immune cell isolation from mouse femur bone marrow. Bio Protoc. 2015;5:e1631.
Phillips EA, Hendricks N, Bucher M, Maloyan A. Vitamin D supplementation improves mitochondrial function and reduces inflammation in placentae of obese women. Front Endocrinol (Lausanne). 2022;13:893848.
Ruffell B, Au A, Rugo HS, Esserman LJ, Hwang ES, Coussens LM. Leukocyte composition of human breast cancer. Proc Natl Acad Sci USA. 2012;109:2796–801.
Article CAS PubMed Google Scholar
Tall AR, Yvan-Charvet L, Westerterp M, Murphy AJ. Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis. Arterioscler Thromb Vasc Biol. 2012;32:2547–52.
Article CAS PubMed Google Scholar
TeSlaa T, Ralser M, Fan J, Rabinowitz JD. The pentose phosphate pathway in health and disease. Nat Metab. 2023;5:1275–89.
Article CAS PubMed Google Scholar
Artyomov MN, Van den Bossche J. Immunometabolism in the Single-Cell Era. Cell Metab. 2020;32:710–25.
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