Dyslipidemia and ANGPTL8 evaluation in young females with Type 1 diabetes mellitus

A. Vetere, A. Choudhary, S.M. Burns, B.K. Wagner, Targeting the pancreatic β-cell to treat diabetes. Nat Rev Drug Discov 13(4), 278–289 (2014)

Article  CAS  PubMed  Google Scholar 

P.A. Seymour, P. Serup, Bulking up on beta cells. N. Engl J Med 369(8), 777–779 (2013)

Article  PubMed  Google Scholar 

P. Yi, J.S. Park, D.A. Melton, Retraction notice to: ANGPTL8: A hormone that controls pancreatic β cell proliferation. Cell 168(1-2), 326 (2017)

Article  CAS  PubMed  Google Scholar 

Y. Jiao, J. Le Lay, M. Yu, A. Naji, K.H. Kaestner, Elevated mouse hepatic ANGPTL8 expression does not increase human β-cell replication in the transplant setting. Diabetes 63(4), 1283–1288 (2014)

Article  CAS  PubMed  PubMed Central  Google Scholar 

D.M. Maahs, N.A. West, J.M. Lawrence, E.J. Mayer-Davis, Epidemiology of type 1 diabetes. Endocrinol Metab Clin North Am 39(3), 481–497 (2010)

Article  PubMed  PubMed Central  Google Scholar 

M. Noorelahi, A. Soubhanneyaz, K. Kasim, Perceptions, barriers, and practices of medical research among students at Taibah College of Medicine, Madinah, Saudi Arabia. Adv Med Educ Pract 6(6), 479–485 (2015). 2015

Article  PubMed  PubMed Central  Google Scholar 

M.A. Abduljabbar, J.M. Aljubeh, A. Amalraj, M.P. Cherian, Incidence trends of childhood type 1 diabetes in eastern Saudi Arabia. Saudi Med J 31(4), 413–418 (2010)

PubMed  Google Scholar 

J. Guy, L. Ogden, R.P. Wadwa et al. Lipid and lipoprotein profiles in youth with and without type 1 diabetes: the SEARCH for Diabetes in Youth case-control study. Diab Care 32(3), 416–420 (2009)

Article  CAS  Google Scholar 

B. Vergès, Dyslipidemia in Type 1 Diabetes: A masked danger. Trends Endocrinol Metab 31(6), 422–434 (2020)

Article  PubMed  Google Scholar 

R. Fagundes Melo, L.F. Laurindo, K.P. Sloan et al. Investigating the Incidence of Dyslipidemia among Brazilian Children and Adolescents Diagnosed with Type 1 Diabetes Mellitus: A Cross-Sectional Study. Diseases 12(3), 45 (2024)

Article  CAS  PubMed  PubMed Central  Google Scholar 

S.H. Kim, I.A. Jung, Y.J. Jeon et al. Serum lipid profiles and glycemic control in adolescents and young adults with type 1 diabetes mellitus. Ann Pediatr Endocrinol Metab 19(4), 191–196 (2014)

Article  PubMed  PubMed Central  Google Scholar 

Z. Fu, F. Yao, A.B. Abou-Samra, R. Zhang, Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family. Biochem Biophys Res Commun 430(3), 1126–1131 (2013)

Article  CAS  PubMed  Google Scholar 

R. Zhang, Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels. Biochem Biophys Res Commun 424(4), 786–792 (2012)

Article  CAS  PubMed  Google Scholar 

A.A. Alrasheed, Dyslipidemia among patients with Type 1 Diabetes and its associated factors in Saudi Arabia: An analytical cross-sectional study. Cureus 14(2), e21923 (2022)

PubMed  PubMed Central  Google Scholar 

L. Mangili, High prevalence of Dyslipidemia in children and adolescents: opportunity for prevention. Arq Bras Cardiol 114(1), 57–58 (2020)

PubMed  PubMed Central  Google Scholar 

S. Bekele, T. Yohannes, A.E. Mohammed, Dyslipidemia and associated factors among diabetic patients attending Durame General Hospital in Southern Nations, Nationalities, and People’s Region. Diab Metab Syndr Obes 10, 265–271 (2017)

Article  CAS  Google Scholar 

Y. Wang, F. Quagliarini, V. Gusarova, J. Gromada, D.M. Valenzuela, J.C. Cohen et al. Mice lacking ANGPTL8 (ANGPTL8) manifest disrupted triglyceride metabolism without impaired glucose homeostasis. Proc Natl Acad Sci USA 110(40), 16109–16114 (2013)

Article  CAS  PubMed  PubMed Central  Google Scholar 

P. Yi, J.S. Park, D.A. Melton, Retraction Notice to: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation. Cell 168(1-2), 326 (2017)

Article  CAS  PubMed  Google Scholar 

P.Y. Chen, W.Y. Gao, J.W. Liou, C.Y. Lin, M.J. Wu, J.H. Yen, Angiopoietin-Like Protein 3 (ANGPTL3) modulates lipoprotein metabolism and Dyslipidemia. Int J Mol Sci 22(14), 7310 (2021)

Article  CAS  PubMed  PubMed Central  Google Scholar 

M. Abu-Farha, D. Sriraman, P. Cherian et al. Circulating ANGPTL8/Betatrophin Is Increased in obesity and reduced after exercise training. PLoS One 11(1), e0147367 (2016)

Article  PubMed  PubMed Central  Google Scholar 

A. Fenzl, B.K. Itariu, L. Kosi, M. Fritzer-Szekeres, A. Kautzky-Willer, T.M. Stulnig et al. Circulating ANGPTL8 correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals. Diabetologia 57(6), 1204–1208 (2014)

Article  CAS  PubMed  Google Scholar 

M. Enteshary, F. Esfarjani, J. Reisi, Comparison of the effects of two different intensities of combined training on Irisin, Betatrophin, and Insulin levels in women with Type 2 Diabetes. Asian J Sports Med 10(2), e68943 (2019)

Article  Google Scholar 

F.E. Dewey, V. Gusarova, R.L. Dunbar, C. O’Dushlaine, C. Schurmann, O. Gottesman, S. McCarthy, C.V. Van Hout, S. Bruse, H.M. Dansky et al. Genetic and pharmacologic inactivation of ANGPTL3 and cardiovascular disease. N. Engl J Med 377, 211–221 (2017)

Article  CAS  PubMed  PubMed Central  Google Scholar 

N.O. Stitziel, A.V. Khera, X. Wang, A.J. Bierhals, A.C. Vourakis, A.E. Sperry, P. Natarajan, D. Klarin, C.A. Emdin, S.M. Zekavat et al. ANGPTL3 deficiency and protection against coronary artery disease. J Am Coll Cardiol 69, 2054–2063 (2017)

Article  CAS  PubMed  PubMed Central  Google Scholar 

D. Espes, J. Lau, P.O. Carlsson, Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes. Diabetologia 57(1), 50–53 (2014)

Article  CAS  PubMed  Google Scholar 

H. Yamada, T. Saito, A. Aoki et al. Circulating betatrophin is elevated in patients with type 1 and type 2 diabetes. Endocr J 62(5), 417–421 (2015)

Article  CAS  PubMed  Google Scholar 

D. Espes, M. Martinell, P.O. Carlsson, Increased circulating betatrophin concentrations in patients with type 2 diabetes. Int J Endocrinol 2014, 323407 (2014)

Article  PubMed  PubMed Central  Google Scholar 

H. Lőrincz, S. Csiha, B. Ratku et al. Gender-dependent associations between Serum Betatrophin levels and Lipoprotein subfractions in diabetic and nondiabetic obese patients. Int J Mol Sci 24(22), 16504 (2023)

Article  PubMed  PubMed Central  Google Scholar 

Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on the detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285: 2486.

U.I. Nwagha, E.J. Ikekpeazu, F.E. Ejezie, E.E. Neboh, I.C. Maduka, Atherogenic index of plasma as useful predictor of cardiovascular risk among postmenopausal women in Enugu. Afr Health Sci 10(3), 248–252 (2010)

CAS  PubMed  PubMed Central  Google Scholar 

World Health Organization Grow Reference Data for 5–19 Years. [(accessed on 20 November 2023)];2008 Available online: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636412/pdf/07-043497.pdf

H. Hu, W. Sun, S. Yu, X. Hong, W. Qian, B. Tang et al. Increased circulating levels of ANGPTL8 in newly diagnosed type 2 diabetic patients. Diab Care 37(10), 2718–2722 (2014)

Article  CAS  Google Scholar 

Z. Fu, F. Berhane, A. Fite, B. Seyoum, A.B. Abou-Samra, R. Zhang, Elevated circulating lipasin/ANGPTL8 in human type 2 diabetes and obesity. Sci Rep. 4, 5013 (2014)

Article  CAS 

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