Mundel P, Heid HW, Mundel TM, Krüger M, Reiser J, Kriz W. Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes. J Cell Biol. 1997;139:193–204.
Article CAS PubMed PubMed Central Google Scholar
Czarnecki K, Haas CA, Bas Orth C, Deller T, Frotscher M. Postnatal development of synaptopodin expression in the rodent hippocampus. J Comp Neurol. 2005;490:133–44.
Article CAS PubMed Google Scholar
Verbich D, Becker D, Vlachos A, Mundel P, Deller T, McKinney RA. Rewiring neuronal microcircuits of the brain via spine head protrusions–a role for synaptopodin and intracellular calcium stores. Acta Neuropathol Commun. 2016;4:38.
Article PubMed PubMed Central Google Scholar
Vlachos A, Ikenberg B, Lenz M, Becker D, Reifenberg K, Bas-Orth C, et al. Synaptopodin regulates denervation-induced homeostatic synaptic plasticity. Proc Natl Acad Sci U S A. 2013;110:8242–7.
Article CAS PubMed PubMed Central Google Scholar
Jedlicka P, Vlachos A, Schwarzacher SW, Deller T. A role for the spine apparatus in LTP and spatial learning. Behav Brain Res. 2008;192:12–9.
Deller T, Korte M, Chabanis S, Drakew A, Schwegler H, Stefani GG, et al. Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci. 2003;100:10494–9.
Article CAS PubMed PubMed Central Google Scholar
Vlachos A, Korkotian E, Schonfeld E, Copanaki E, Deller T, Segal M. Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons. J Neurosci. 2009;29:1017–33.
Article CAS PubMed PubMed Central Google Scholar
Segal M, Vlachos A, Korkotian E. The spine apparatus, Synaptopodin, and dendritic spine plasticity. Neuroscientist. 2010;16:125–31.
Article CAS PubMed Google Scholar
Jedlicka P, Deller T. Understanding the role of synaptopodin and the spine apparatus in hebbian synaptic plasticity– new perspectives and the need for computational modeling. Neurobiol Learn Mem. 2017;138:21–30.
Article CAS PubMed Google Scholar
Speranza L, Inglebert Y, De Sanctis C, Wu PY, Kalinowska M, McKinney RA, et al. Stabilization of spine synaptopodin by mGluR1 is required for mGluR-LTD. J Neurosci. 2022;42:1666–78.
Article CAS PubMed PubMed Central Google Scholar
Wu PY, Ji L, De Sanctis C, Francesconi A, Inglebert Y, McKinney RA. Loss of synaptopodin impairs mGluR5 and protein synthesis-dependent mGluR-LTD at CA3-CA1 synapses. PNAS Nexus. 2024;3:pgae062. https://doi.org/10.1093/pnasnexus/pgae062
Dudek SM, Bear MF. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proc Natl Acad Sci. 1992;89:4363–7.
Article CAS PubMed PubMed Central Google Scholar
Malenka RC, Bear MF. LTP and LTD. Neuron. 2004;44:5–21.
Article CAS PubMed Google Scholar
Holbro N, Grunditz Å, Oertner TG. Differential distribution of endoplasmic reticulum controls metabotropic signaling and plasticity at hippocampal synapses. Proc Natl Acad Sci. 2009;106:15055–60.
Article CAS PubMed PubMed Central Google Scholar
Zhang X-l, Poschel B, Faul C, Upreti C, Stanton PK, Mundel P. Essential role for Synaptopodin in dendritic spine plasticity of the developing Hippocampus. J Neurosci. 2013;33:12510–8.
Article CAS PubMed PubMed Central Google Scholar
Dan Y, Poo M-M. Spike timing-dependent plasticity: from synapse to Perception. Physiol Rev. 2006;86:1033–48.
Bi G, Poo M. Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci. 1998;18:10464–72.
Article CAS PubMed PubMed Central Google Scholar
Debanne D, Gähwiler BH, Thompson SM. Long-term synaptic plasticity between pairs of individual CA3 pyramidal cells in rat hippocampal slice cultures. J Physiol. 1998;507:237–47.
Article CAS PubMed PubMed Central Google Scholar
Debanne D, Gähwiler BH, Thompson SM. Cooperative interactions in the induction of long-term potentiation and depression of synaptic excitation between hippocampal CA3-CA1 cell pairs in vitro. Proc Natl Acad Sci U S A. 1996;93:11225–30.
Article CAS PubMed PubMed Central Google Scholar
Debanne D, Guérineau NC, Gähwiler BH, Thompson SM. Paired-pulse facilitation and depression at unitary synapses in rat hippocampus: quantal fluctuation affects subsequent release. J Physiol. 1996;491:163–76.
Article CAS PubMed PubMed Central Google Scholar
Markram H, Lübke J, Frotscher M, Sakmann B. Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs. Science. 1997;275:213–5.
Article CAS PubMed Google Scholar
Andrade-Talavera Y, Duque-Feria P, Paulsen O, Rodríguez-Moreno A. Presynaptic spike timing-dependent long-term depression in the mouse Hippocampus. Cereb Cortex N Y N 1991. 2016;26:3637–54.
Inglebert Y, Debanne D. Calcium and Spike Timing-Dependent Plasticity. Front Cell Neurosci. 2021;15:727336.
Article CAS PubMed PubMed Central Google Scholar
Debanne D, Inglebert Y. Spike timing-dependent plasticity and memory. Curr Opin Neurobiol. 2023;80:102707.
Article CAS PubMed Google Scholar
Feldman DE. The spike-timing dependence of plasticity. Neuron. 2012;75:556–71.
Article CAS PubMed PubMed Central Google Scholar
Inglebert Y, Aljadeff J, Brunel N, Debanne D. Synaptic plasticity rules with physiological calcium levels. Proc Natl Acad Sci U S A. 2020;117:33639–48.
Article CAS PubMed PubMed Central Google Scholar
Wittenberg GM. Malleability of spike-timing-dependent plasticity at the CA3-CA1 synapse. J Neurosci. 2006;26:6610–7.
Article CAS PubMed PubMed Central Google Scholar
Henley JM, Wilkinson KA. Synaptic AMPA receptor composition in development, plasticity and disease. Nat Rev Neurosci. 2016;17:337–50.
Article CAS PubMed Google Scholar
Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci. 2013;14:383–400.
Article CAS PubMed Google Scholar
Mockett B, Coussens C, Abraham WC. NMDA receptor-mediated metaplasticity during the induction of long-term depression by low-frequency stimulation: priming of LTD during low frequency stimulation. Eur J Neurosci. 2002;15:1819–26.
Petersen CCH, Malenka RC, Nicoll RA, Hopfield JJ. All-or-none potentiation at CA3-CA1 synapses. Proc Natl Acad Sci. 1998;95:4732–7.
Article CAS PubMed PubMed Central Google Scholar
O’Connor DH, Wittenberg GM, Wang SS-H. Graded bidirectional synaptic plasticity is composed of switch-like unitary events. Proc Natl Acad Sci. 2005;102:9679–84.
Article PubMed PubMed Central Google Scholar
Froemke RC, Tsay IA, Raad M, Long JD, Dan Y. Contribution of individual spikes in Burst-Induced Long-Term synaptic modification. J Neurophysiol. 2006;95:1620–9.
Forsberg M, Seth H, Björefeldt A, Lyckenvik T, Andersson M, Wasling P, et al. Ionized calcium in human cerebrospinal fluid and its influence on intrinsic and synaptic excitability of hippocampal pyramidal neurons in the rat. J Neurochem. 2019;149:452–70.
Article CAS PubMed Google Scholar
Jedlicka P, Schwarzacher SW, Winkels R, Kienzler F, Frotscher M, Bramham CR, et al. Impairment of in vivo theta-burst long-term potentiation and network excitability in the dentate gyrus of synaptopodin-deficient mice lacking the spine apparatus and the cisternal organelle. Hippocampus. 2009;19:130–40.
Article CAS PubMed Google Scholar
Aloni E, Verbitsky S, Kushnireva L, Korkotian E, Segal M. Increased excitability of hippocampal neurons in mature synaptopodin-knockout mice. Brain Struct Funct. 2021;226:2459–66.
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