Diagnostic Criteria for Oral Epithelial Dysplasia: Predicting Malignant Transformation

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74:229–263

Article  PubMed  Google Scholar 

Warnakulasuriya S, Kujan O, Aguirre-Urizar JM, Bagan JV, González-Moles MÁ, Kerr AR et al (2021) Oral potentially malignant disorders: a consensus report from an international seminar on nomenclature and classification, convened by the WHO collaborating centre for oral Cancer. Oral Dis 27:1862–1880

Article  PubMed  Google Scholar 

Warnakulasuriya S, Johnson NW, van der Waal I (2007) Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med 36:575–580

Article  CAS  PubMed  Google Scholar 

Kalavrezos N, Scully C (2015) Mouth Cancer for clinicians Part 6: potentially malignant disorders. Dent Update 42:866–868,871–874,877

Article  PubMed  Google Scholar 

van der Waal I (2009) Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncol 45:317–323

Article  PubMed  Google Scholar 

Reibel J, Gale N, Hille J et al (2017) Oral potentially malignant disorders and oral epithelial dysplasia. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ et al (eds) WHO classification of tumours of the head and neck. 4 th. IARC, Lyon (France)

Google Scholar 

Kujan O, Oliver RJ, Khattab A, Roberts SA, Thakker N, Sloan P (2006) Evaluation of a new binary system of grading oral epithelial dysplasia for prediction of malignant transformation. Oral Oncol 42:987–993

Article  PubMed  Google Scholar 

Embaló B, Miguel AFP, Konrath AC, Modolo F, Rivero ERC (2023) Evaluation of two classification systems for oral epithelial dysplasia. Oral Dis 29:100–104

Article  PubMed  Google Scholar 

Mahmood H, Bradburn M, Rajpoot N, Islam NM, Kujan O, Khurram SA (2022) Prediction of malignant transformation and recurrence of oral epithelial dysplasia using architectural and cytological feature specific prognostic models. Mod Pathol 35:1151–1159

Article  PubMed  PubMed Central  Google Scholar 

Muller S, Tilakaratne WM (2022) Update from the 5th Edition of the World Health Organization Classification of Head and Neck tumors: Tumours of the oral cavity and Mobile Tongue. Head Neck Pathol 16:54–62

Article  PubMed  PubMed Central  Google Scholar 

WHO classification of Tumors Editorial Board. Head and neck tumours [Internet; beta version ahead of print]. [Internet]. 5th; vol 9 ed. Lyon (France): International Agency for Research on Cancer, 2022 (2022) Available from: http://tumourclassification.iarc.who.int/chapters/52

Speight PM, Abram TJ, Floriano PN, James R, Vick J, Thornhill MH et al (2015) Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials. Oral Surg Oral Med Oral Pathol Oral Radiol.;120:474– 82.e2.

Zhang L, Cheung KJJ, Lam WL, Cheng X, Poh C, Priddy R et al (2001) Increased genetic damage in oral leukoplakia from high risk sites: potential impact on staging and clinical management. Cancer 91:2148–2155

Article  CAS  PubMed  Google Scholar 

Napier SS, Speight PM (2008) Natural history of potentially malignant oral lesions and conditions: an overview of the literature. J Oral Pathol Med 37:1–10

Article  PubMed  Google Scholar 

Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG (2009) Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inf 42:377–381

Article  Google Scholar 

Warnakulasuriya S, Reibel J, Bouquot J, Dabelsteen E (2008) Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement. J Oral Pathol Med 37:127–133

Article  CAS  PubMed  Google Scholar 

Ranganathan K, Kavitha L, Sharada P, Bavle RM, Rao RS, Pattanshetty SM et al (2020) Intra-observer and inter-observer variability in two grading systems for oral epithelial dysplasia: a multi-centre study in India. J Oral Pathol Med 49:948–955

Article  CAS  PubMed  Google Scholar 

Nankivell P, Williams H, Matthews P, Suortamo S, Snead D, McConkey C et al (2013) The binary oral dysplasia grading system: validity testing and suggested improvement. Oral Surg Oral Med Oral Pathol Oral Radiol 115:87–94

Article  PubMed  Google Scholar 

de Freitas Silva BS, Batista DCR, de Souza Roriz CF, Silva LR, Normando AGC, Dos Santos Silva AR et al (2021) Binary and WHO dysplasia grading systems for the prediction of malignant transformation of oral leukoplakia and erythroplakia: a systematic review and meta-analysis. Clin Oral Investig 25:4329–4340

Article  PubMed  Google Scholar 

Dost F, Lê Cao K, Ford PJ, Ades C, Farah CS (2014) Malignant transformation of oral epithelial dysplasia: a real-world evaluation of histopathologic grading. Oral Surg Oral Med Oral Pathol Oral Radiol 117:343–352

Article  CAS  PubMed  Google Scholar 

Sperandio M, Warnakulasuriya S, Soares AB, Passador-Santos F, Mariano FV, Lima CSP et al (2023) Oral epithelial dysplasia grading: comparing the binary system to the traditional 3-tier system, an actuarial study with malignant transformation as outcome. J Oral Pathol Med 52:418–425

Article  PubMed  Google Scholar 

Odell E, Kujan O, Warnakulasuriya S, Sloan P (2021) Oral epithelial dysplasia: Recognition, grading and clinical significance. Oral Dis 27:1947–1976

Article  PubMed  Google Scholar 

Gupta PC, Mehta FS, Daftary DK, Pindborg JJ, Bhonsle RB, Jalnawalla PN et al (1980) Incidence rates of oral cancer and natural history of oral precancerous lesions in a 10-year follow-up study of Indian villagers. Community Dent Oral Epidemiol 8:283–333

Article  CAS  PubMed  Google Scholar 

Holmstrup P, Vedtofte P, Reibel J, Stoltze K (2006) Long-term treatment outcome of oral premalignant lesions. Oral Oncol 42:461–474

Article  CAS  PubMed  Google Scholar 

Comments (0)

No login
gif