A highly practical and efficient Cp*Co(III)-catalyzed C–H alkylation/alkenylation reaction of anilides with maleimides and acrylates was developed, during which weakly coordinating amide carbonyl group functioned as the directing group. This approach features high efficiency, good functional group tolerance, and broad substrate scope, and a variety of 3-substituted succinimides and ortho-alkenylated anilides were synthesized in moderate to excellent yields. Furthermore, the reaction is highly selective, giving the mono-ortho- alkylated/alkenylated products only. In addition, synthetic transformations of the 3-substituted succinimide products demonstrate the practicability of the reaction.

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