Comparative efficacy of probiotic mixture Bifidobacterium longum KABP042 plus Pediococcus pentosaceus KABP041 vs. Limosilactobacillus reuteri DSM17938 in the management of infant colic: a randomized clinical trial

Vandenplas Y, Abkari A, Bellaiche M, Benninga M, Chouraqui JP, Osatakul S, Salvatore S, Shamir R, Staiano A, Szajewska H, Thapar N (2015) Prevalence and health outcomes of functional gastrointestinal symptoms in infants from birth to 12 months of age. J Pediatr Gastroenterol Nutr 61:531–537. https://doi.org/10.1097/MPG.0000000000000949

Article  PubMed  PubMed Central  Google Scholar 

Benninga MA, Nurko S, Faure C, Hyman PE, St James Roberts I, Schechter NL (2016) Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology 150:1443-1455.e2. https://doi.org/10.1053/j.gastro.2016.02.016

Article  Google Scholar 

Sung V, D’Amico F, Cabana MD, Chau K, Koren G, Savino F, Szajewska H, Deshpande G, Dupont C, Indrio F, Mentula S, Partty A, Tancredi D (2018) Lactobacillus reuteri to treat infant colic: a meta-analysis. Pediatrics 141:e20171811. https://doi.org/10.1542/peds.2017-1811

Article  PubMed  Google Scholar 

Indrio F, Dargenio VN, Francavilla R, Szajewska H, Vandenplas Y (2023) Infantile colic and long-term outcomes in childhood: a narrative synthesis of the evidence. Nutrients 15:615. https://doi.org/10.3390/nu15030615

Article  PubMed  PubMed Central  Google Scholar 

Rhoads JM, Collins J, Fatheree NY, Hashmi SS, Taylor CM, Luo M, Hoang TK, Gleason WA, Van Arsdall MR, Navarro F, Liu Y (2018) Infant colic represents gut inflammation and dysbiosis. J Pediatr 203:55-61.e3. https://doi.org/10.1016/j.jpeds.2018.07.042

Article  PubMed  Google Scholar 

Zeevenhooven J, Browne PD, L’Hoir MP, de Weerth C, Benninga MA (2018) Infant colic: mechanisms and management. Nat Rev Gastroenterol Hepatol 15:479–496. https://doi.org/10.1038/s41575-018-0008-7

Article  PubMed  Google Scholar 

Sommermeyer H, Bernatek M, Pszczola M, Krauss H, Piatek J (2022) Supporting the diagnosis of infantile colic by a point of care measurement of fecal calprotectin. Front Pediatr 10:. https://doi.org/10.3389/fped.2022.978545

De Weerth C, Fuentes S, Puylaert P, De Vos WM (2013) Intestinal microbiota of infants with colic: development and specific signatures. Pediatrics 131:e550–e558. https://doi.org/10.1542/peds.2012-1449

Article  PubMed  Google Scholar 

Savino F, Cordisco L, Tarasco V, Calabrese R, Palumeri E, Matteuzzi D (2009) Molecular identification of coliform bacteria from colicky breastfed infants. Acta Paediatr 98:1582–1588. https://doi.org/10.1111/j.1651-2227.2009.01419.x

Article  CAS  PubMed  Google Scholar 

FAO/WHO (2002) Report of a Joint FAO/WHO Working group on drafting guidelines for the evaluation of probiotics in food. Ontario

Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, Morelli L, Canani RB, Flint HJ, Salminen S, Calder PC, Hill MES, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, Morelli L, Canani RB, Flint HJ, Salminen S, Calder PC, Sanders ME (2014) Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol 11:506–514. https://doi.org/10.1038/nrgastro.2014.66

Article  PubMed  Google Scholar 

Ellwood J, Draper-Rodi J, Carnes D (2020) Comparison of common interventions for the treatment of infantile colic: a systematic review of reviews and guidelines. BMJ Open 10:e035405. https://doi.org/10.1136/bmjopen-2019-035405

Article  PubMed  PubMed Central  Google Scholar 

Skonieczna-żydecka K, Janda K, Kaczmarczyk M, Marlicz W, Łoniewski I, Łoniewska B (2020) The effect of probiotics on symptoms, gut microbiota and inflammatory markers in infantile colic: a systematic review, meta-analysis and meta-regression of randomized controlled trials. J Clin Med 9:999. https://doi.org/10.3390/jcm9040999

Article  CAS  PubMed  PubMed Central  Google Scholar 

Savino F, Cordisco L, Tarasco V, Palumeri E, Calabrese R, Oggero R, Roos S, Matteuzzi D (2010) Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. Pediatrics 126:e526–e533. https://doi.org/10.1542/peds.2010-0433

Article  PubMed  Google Scholar 

Szajewska H, Gyrczuk E, Horvath A (2013) Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trial. J Pediatr 162:257–262. https://doi.org/10.1016/j.jpeds.2012.08.004

Article  PubMed  Google Scholar 

Chau K, Lau E, Greenberg S, Jacobson S, Yazdani-Brojeni P, Verma N, Koren G (2015) Probiotics for infantile colic: a randomized, double-blind, placebo-controlled trial investigating Lactobacillus reuteri DSM 17938. J Pediatr 166:74–78. https://doi.org/10.1016/j.jpeds.2014.09.020

Article  CAS  PubMed  Google Scholar 

Mi GL, Zhao L, Qiao DD, Kang WQ, Tang MQ, Xu JK (2015) Effectiveness of Lactobacillus reuteri in infantile colic and colicky induced maternal depression: a prospective single blind randomized trial. Antonie Van Leeuwenhoek 107:1547–1553. https://doi.org/10.1007/s10482-015-0448-9

Article  PubMed  Google Scholar 

Guarner F, Sanders ME, Szajewska H, Cohen H, Eliakim R, Herrera C, Karakan T, Merenstein D, Piscoya A, Ramakrishna B, Salminen S (2023) World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics. In: World Gastroenterol. Organ. https://www.worldgastroenterology.org/guidelines/probiotics-and-prebiotics/probiotics-and-prebiotics-english. Accessed 19 Dec 2023

Szajewska H, Canani RB, Domellöf M, Guarino A, Hojsak I, Indrio F, Lo VA, Mihatsch WA, Mosca A, Orel R, Salvatore S, Shamir R, van den Akker CHP, van Goudoever JB, Vandenplas Y, Weizman Z, Canani RB, Guarino A, Dinleyci EC, Domellöf M, Indrio F, Hojsak I, Gutiierez P, Kolacek S, Mihatsch WA, Mosca A, Orel R, Salvatore S, Shamir R, Szajewska H, Vandenplas Y, van den Akker CHP, van Goudoever JB, Weizman Z (2023) Probiotics for the management of pediatric gastrointestinal disorders. Position Paper of the ESPGHAN Special Interest Group on Gut Microbiota and Modifications. J Pediatr Gastroenterol Nutr 76:232–247. https://doi.org/10.1097/MPG.0000000000003633

Article  PubMed  Google Scholar 

Santas J, Fuentes MC, Tormo R, Guayta-Escolies R, Lázaro E, Cuñé J (2015) Pediococcus pentosaceus CECT 8330 and Bifidobacterium longum CECT 7894 show a trend towards lowering infantile excessive crying syndrome in a pilot clinical trial. Int J Pharma Bio Sci 6:458–466

Google Scholar 

Chen K, Liu C, Li H, Lei Y, Zeng C, Xu S, Li J, Savino F (2021) Infantile colic treated with Bifidobacterium longum CECT7894 and Pediococcus pentosaceus CECT8330: a randomized, double-blind, placebo-controlled trial. Front Pediatr 9:635176. https://doi.org/10.3389/fped.2021.635176

Article  PubMed  Google Scholar 

Schulz KF, Altman DG, David Moher for the CONSORT Group, Abstract (2010) CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. BMC Med 8:18. https://doi.org/10.1186/1741-7015-8-18

Article  PubMed  PubMed Central  Google Scholar 

Barr RG, Kramer MS, Boisjoly C, McVey-White L, Pless IB (1988) Parental diary of infant cry and fuss behaviour. Arch Dis Child 63:380–387. https://doi.org/10.1136/adc.63.4.380

Article  CAS  PubMed  Google Scholar 

Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361–370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x

Article  CAS  PubMed  Google Scholar 

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (2019) Cochrane handbook for systematic reviews of interventions, 2nd edn. John Wiley & Sons, Chichester (UK)

Book  Google Scholar 

dos Reis P, Buzzo Zermiani A, Peçanha P, de Paula Soares AL, da Silva Guedes de Moura BL, Arpini Miguel ER, Dias Ghiraldi Lopes L, de Carvalho Scharf Santana N, da Silva Santos T, Galhardo Demarchi I, Juarez Teixeira J, (2021) Evidence of Lactobacillus reuteri to reduce colic in breastfed babies: systematic review and meta-analysis. Complement Ther Med 63:102781. https://doi.org/10.1016/j.ctim.2021.102781

Article  Google Scholar 

Sung V, Hiscock H, Tang MLK, Mensah FK, Nation ML, Satzke C, Heine RG, Stock A, Barr RG, Wake M (2014) Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial. BMJ 348:g2107. https://doi.org/10.1136/bmj.g2107

Article  PubMed  Google Scholar 

Savino F, Garro M, Montanari P, Galliano I, Bergallo M (2018) Crying time and RORγ/FOXP3 expression in Lactobacillus reuteri DSM17938-treated infants with colic: a randomized trial. J Pediatr 192:171-177.e1. https://doi.org/10.1016/j.jpeds.2017.08.062

Article  CAS  PubMed  Google Scholar 

Indrio F, Di MA, Riezzo G, Civardi E, Intini C, Corvaglia L, Ballardini E, Bisceglia M, Cinquetti M, Brazzoduro E, Del VA, Tafuri S, Francavilla R (2014) Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation a randomized clinical trial. JAMA Pediatr 168:228–233. https://doi.org/10.1001/jamapediatrics.2013.4367

Article  PubMed  Google Scholar 

Lavalle L, Sauvageot N, Cercamondi CI, Jankovic I, Egli D, Vandenplas Y (2023) Limosilactobacillus reuteri DSM 17938-containing infant formulas and the associations with gastrointestinal tolerance: a cross-sectional observational study. Nutrients 15:530. https://doi.org/10.3390/nu15030530

Article  PubMed  PubMed Central  Google Scholar 

Stewart CJ, Ajami NJ, O’Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni HV, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, Rewers M, Hagopian W, Toppari J, Ziegler AG, She JX, Akolkar B, Lernmark A, Hyoty H, Vehik K, Krischer JP, Petrosino JF (2018) Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature 562:583–588. https://doi.org/10.1038/s41586-018-0617-x

Article 

Comments (0)

No login
gif