GBD Disease and Injury Incidence and Prevalence Collaborators (2018) Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet 392(10159):1789–1858. https://doi.org/10.1016/S0140-6736(18)32279-7
Ambrosy AP, Fonarow GC, Butler J, Chioncel O, Greene SJ, Vaduganathan M, Nodari S, Lam CSP, Sato N, Shah AN, Gheorghiade M (2014) The global health and economic burden of hospitalizations for heart failure: Lessons learned from hospitalized heart failure registries. J Am Coll Cardiol 63(12):1123–1133. https://doi.org/10.1016/j.jacc.2013.11.053
Lund LH, Carrero JJ, Farahmand B, Henriksson KM, Jonsson A, Jernberg T, Dahlstrom U (2017) Association between enrolment in a heart failure quality registry and subsequent mortality-a nationwide cohort study. Eur J Heart Fail 19(9):1107–1116. https://doi.org/10.1002/ejhf.762
Crespo-Leiro MG, Metra M, Lund LH et al (2018) Advanced heart failure: A position statement of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 20(11):1505–1535. https://doi.org/10.1002/ejhf.1236
Wang Z, Yang T, Fu H (2021) Prevalence of diabetes and hypertension and their interaction effects on cardio-cerebrovascular diseases: A cross-sectional study. BMC Public Health 21(1):1224. https://doi.org/10.1186/s12889-021-11122-y
Article CAS PubMed PubMed Central Google Scholar
Borlaug BA, Redfield MM (2011) Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum. Circulation 123(18):2006–2013. https://doi.org/10.1161/CIRCULATIONAHA.110.954388. discussion 2014
Article PubMed PubMed Central Google Scholar
Simmonds SJ, Cuijpers I, Heymans S, Jones EAV (2020) Cellular and molecular differences between HFpEF and HFrEF: A step ahead in an improved pathological understanding. Cells 9(1):242. https://doi.org/10.3390/cells9010242
Article CAS PubMed PubMed Central Google Scholar
Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB (2020) Research priorities for heart failure with preserved ejection fraction: National Heart, Lung, and Blood Institute Working Group Summary. Circulation 141(12):1001–1026. https://doi.org/10.1161/CIRCULATIONAHA.119.041886
Article PubMed PubMed Central Google Scholar
Miller WL, Grill DE, Borlaug BA (2013) Clinical features, hemodynamics, and outcomes of pulmonary hypertension due to chronic heart failure with reduced ejection fraction: pulmonary hypertension and heart failure. JACC Heart Fail 1(4):290–299. https://doi.org/10.1016/j.jchf.2013.05.001
Lam CS, Solomon SD (2014) The middle child in heart failure: Heart failure with mid-range ejection fraction (40–50%). Eur J Heart Fail 16(10):1049–1055. https://doi.org/10.1002/ejhf.159
Dunlay SM, Roger VL, Weston SA, Jiang R, Redfield MM (2012) Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction. Circ Heart Fail 5(6):720–726. https://doi.org/10.1161/CIRCHEARTFAILURE.111.966366
Article PubMed PubMed Central Google Scholar
Tromp J, Khan MAF, Mentz RJ, O’Connor CM, Metra M, Dittrich HC, Ponikowski P, Teerlink JR, Cotter G, Davison B, Cleland JGF, Givertz MM, Bloomfield DM, Van Veldhuisen DJ, Hillege HL, Voors AA, van der Meer P (2017) Biomarker profiles of acute heart failure patients with a mid-range ejection fraction. JACC Heart Fail 5(7):507–517. https://doi.org/10.1016/j.jchf.2017.04.007
Adamo L, Rocha-Resende C, Prabhu SD, Mann DL (2021) Publisher correction: Reappraising the role of inflammation in heart failure. Nat Rev Cardiol 18(10):735. https://doi.org/10.1038/s41569-021-00534-3
Reddy YNV, Rikhi A, Obokata M, Shah SJ, Lewis GD, AbouEzzedine OF, Dunlay S, McNulty S, Chakraborty H, Stevenson LW, Redfield MM, Borlaug BA (2020) Quality of life in heart failure with preserved ejection fraction: Importance of obesity, functional capacity, and physical inactivity. Eur J Heart Fail 22(6):1009–1018. https://doi.org/10.1002/ejhf.1788
Article CAS PubMed Google Scholar
Fernandez-Garcia V, Gonzalez-Ramos S, Martin-Sanz P, Castrillo A, Bosca L (2020) Contribution of extramedullary hematopoiesis to atherosclerosis. The spleen as a neglected hub of inflammatory cells. Front Immunol 11:586527. https://doi.org/10.3389/fimmu.2020.586527
Article CAS PubMed PubMed Central Google Scholar
O’Neill HC, Lim HK, Periasamy P, Kumarappan L, Tan JKH, O’Neill TJ (2019) Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis. PLoS ONE 14(10):e0223416. https://doi.org/10.1371/journal.pone.0223416
Article CAS PubMed PubMed Central Google Scholar
Kim CH (2010) Homeostatic and pathogenic extramedullary hematopoiesis. J Blood Med 1:13–19. https://doi.org/10.2147/JBM.S7224
Article PubMed PubMed Central Google Scholar
Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ (2009) Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 325(5940):612–616. https://doi.org/10.1126/science.1175202
Article CAS PubMed PubMed Central Google Scholar
von Haehling S, Ebner N, Evertz R, Ponikowski P, Anker SD (2019) Iron deficiency in heart failure: An overview. JACC Heart Fail 7(1):36–46. https://doi.org/10.1016/j.jchf.2018.07.015
Ponikowski P, Voors AA, Anker SD et al (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 37(27):2129–2200. https://doi.org/10.1093/eurheartj/ehw128
Heidenreich PA, Bozkurt B, Aguilar D et al (2022) 2022 AHA/ACC/HFSA guideline for the management of heart failure: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol 79(17):e263–e421. https://doi.org/10.1016/j.jacc.2021.12.012
Jankowska EA, Rozentryt P, Witkowska A, Nowak J, Hartmann O, Ponikowska B, Borodulin-Nadzieja L, Banasiak W, Polonski L, Filippatos G, McMurray JJ, Anker SD, Ponikowski P (2010) Iron deficiency: An ominous sign in patients with systolic chronic heart failure. Eur Heart J 31(15):1872–1880. https://doi.org/10.1093/eurheartj/ehq158
Article CAS PubMed Google Scholar
von Haehling S, Gremmler U, Krumm M, Mibach F, Schon N, Taggeselle J, Dahm JB, Angermann CE (2017) Prevalence and clinical impact of iron deficiency and anaemia among outpatients with chronic heart failure: The PrEP Registry. Clin Res Cardiol 106(6):436–443. https://doi.org/10.1007/s00392-016-1073-y
Camaschella C (2017) New insights into iron deficiency and iron deficiency anemia. Blood Rev 31(4):225–233. https://doi.org/10.1016/j.blre.2017.02.004
Article CAS PubMed Google Scholar
Klei TRL, Dalimot J, Nota B, Veldthuis M, Mul FPJ, Rademakers T, Hoogenboezem M, Nagelkerke SQ, van IJcken WFJ, Oole E, Svendsen P, Moestrup SK, van Alphen FPJ, Meijer AB, Kuijpers TW, van Zwieten R, van Bruggen R (2020) Hemolysis in the spleen drives erythrocyte turnover. Blood 136(14):1579–1589. https://doi.org/10.1182/blood.2020005351
Article CAS PubMed Google Scholar
Triposkiadis F, Giamouzis G, Parissis J, Starling RC, Boudoulas H, Skoularigis J, Butler J, Filippatos G (2016) Reframing the association and significance of co-morbidities in heart failure. Eur J Heart Fail 18(7):744–758. https://doi.org/10.1002/ejhf.600
Cappellini MD, Motta I (2015) Anemia in clinical practice-definition and classification: Does hemoglobin change with aging? Semin Hematol 52(4):261–269. https://doi.org/10.1053/j.seminhematol.2015.07.006
Comments (0)