Advances in understanding and exploiting Siglec–glycan interactions

Siglecs

sialic-acid-binding immunoglobulin-type lectins

SAMP

self-associated molecular pattern

ITIM

immunoreceptor-tyrosine-based inhibitory motif

GlcNAc

N-acetyl glucosamine

STD-NMR

saturation transfer difference nuclear magnetic resonance

CRISPR Screen

Clustered Regularly Interspaced Short Palindromic Repeats screen

MYC oncogene

myelocytomatosis oncogene

Neu-5Ac

Cytidine-5′-monophospho-N-acetylneuraminic acid

COIN-nMS

Concentration-independent native mass spectrometry

NK cells

natural killer cells

COVID-19

Coronavirus disease 2019

CAR

chimeric antigen receptor

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