Gut-brain axis
Sepsis-associated encephalopathy
Vagus nerve
Neuroendocrine
Neuroimmune
AbbreviationsACTHadrenocorticotropic hormone
AHRarylhydrocarbon receptor
BDNFbrain-derived neurotrophic factor
CARScompensatory anti-inflammatory response syndrome
CNScentral nervous system
CRHcorticotropin-releasing hormone
DAMPsdamage-associated molecular patterns
ECCsenterochromaffin cells
FMTfecal microbiota transplantation
FXRnuclear farnesoid X receptors
GM-CSFgranulocyte-macrophage colony-stimulating factor
GPBAR-1G protein-coupled BA receptor 1
HMGB1high mobility group box 1
HPAhypothalamic-pituitary-adrenal
IECsintestinal epithelial cells
IGF-1insulin-like growth factor 1
iNOSinducible nitric oxide synthase
LAMPlysosomal-associated membrane protein-1
MAMPsmicrobial-associated molecular patterns
MMP12matrix metalloproteinase 12
NADPHnicotinamide adenine dinucleotide phosphate
NODnucleotide-binding oligomerization domain
Nrf2nuclear factor erythroid factor 2
NTSnucleus tractus solitaris
PAMPspathogen-associated molecular patterns
PMNspolymorphonuclear leukocytes
PSD95postsynaptic density-95
ROSreactive oxygen species
SAEsepsis-associated encephalopathy
SCFAsshort-chain fatty acids
SDVsubdiaphragmatic vagotomy
TNF-αtumor necrosis factor-alpha
TRAILTNF-related apoptosis-inducing ligand
TRIFToll-interleukin-1 receptor (TIR)-domain-containing adaptor-inducing IFN-beta
VEGFvascular endothelial growth factor
γ-GABAγ-aminobutyric acid
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