Prospects for liquid biopsy using microRNA and extracellular vesicles in breast cancer

Machii R, Takahashi H. Japanese cancer screening programs during the COVID-19 pandemic: changes in participation between 2017–2020. Cancer Epidemiol. 2023;82: 102313.

Article  PubMed  Google Scholar 

Srivastava S, Koay EJ, Borowsky AD, et al. Cancer overdiagnosis: a biological challenge and clinical dilemma. Nat Rev cancer. 2019;19:349–58.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xie W, Suryaprakash S, Wu C, Rodriguez A, Fraterman S. Trends in the use of liquid biopsy in oncology. Nat Rev Drug Discov. 2023;22(8):612–3.

Article  CAS  PubMed  Google Scholar 

Matsuzaki J, Ochiya T. Circulating microRNAs: Next-generation cancer detection. Keio J Med. 2020;69:88–96.

Article  CAS  PubMed  Google Scholar 

Matsuzaki J, Kato K, Oono K, Tsuchiya N, Sudo K, Shimomura A, et al. Project team for development and diagnostic technology for detection of miRNA in body fluids. Prediction of tissue-of-origin of early stage cancers using serum miRNomes. JNCI Cancer Spectr. 2023;7:pkac080.

Article  PubMed  Google Scholar 

Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, et al. Novel combination of serum microRNA for detecting breast cancer in the early stage. Cancer Sci. 2016;107:326–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shiino S, Matsuzaki J, Shimomura A, Kawauchi J, Takizawa S, Sakamoto H, et al. Serum miRNA-based prediction of axillary lymph node metastasis in breast cancer. Clin Cancer Res. 2019;25:1817–27.

Article  CAS  PubMed  Google Scholar 

Sato J, Shimomura A, Kawauchi J, Matsuzaki J, Yamamoto Y, Takizawa S, et al. Brain metastasis-related microRNAs in patients with advanced breast cancer. PLoS ONE. 2019;14: e0221538.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Satomi-Tsushita N, Shimomura A, Matsuzaki J, Yamamoto Y, Kawauchi J, Takizawa S, et al. Serum microRNA-based prediction of responsiveness to eribulin in metastatic breast cancer. PLoS ONE. 2019;14: e0222024.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Noda-Narita S, Shimomura A, Tanabe Y, Kawauchi J, Matsuzaki J, Takizawa S. Peripheral neuropathy from paclitaxel: risk prediction by serum microRNAs. BMJ Support Palliat Care. 2020. https://doi.org/10.1136/bmjspcare-2019-001900.

Article  PubMed  Google Scholar 

Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9:654.

Article  CAS  PubMed  Google Scholar 

Fijita Y, Yoshioka Y, Ochiya T. Extracellular vesicle transfer of cancer pathogenic compo- nents. Cancer Sci. 2016;107:385.

Article  Google Scholar 

Kosaka N, Fujita Y, Yoshioka Y, Ochiya T. Versatile roles of extracellular vesicles in cancer. J Clin Invest. 2016;126:1163–72.

Article  PubMed  PubMed Central  Google Scholar 

Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, Ochiya T. Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem. 2010;285:17442–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Villarroya-Beltri C, Baixauli F, Gutierrez-Vazquez C, Sanchez-Madrid F, Mittelbrunn F. Sorting it out: regulation of exosome loading. Semin Cancer Biol. 2014;28:3–13.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yoshioka Y, Konishi Y, Kosaka N, Katsuda T, Kato T, Ochiya T. Comparative marker analysis of extracellular vesicles in different human cancer types. J Extracell Vesicles. 2013;2:20424.

Article  Google Scholar 

Kawamura Y, Yamamoto Y, Sato TA, Ochiya T. Extracellular vesicles as trans-genomic agents: emerging roles in disease and evolution. Cancer Sci. 2017;108:824–30.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Q, Peng F, Chen JJIJOMS. The role of exosomal microRNAs in the tumor microenvironment of breast cancer. Int J Mol Sci. 2019;20:3884.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tominaga N, Kosaka N, Ono M, Katsuda T, Yoshioka Y, Tamura K, Lötvall J, Nakagama H, Ochiya T. Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. Nat Commun. 2015;6:6716.

Article  CAS  PubMed  Google Scholar 

Cappariello A, Capulli M. The vicious cycle of breast cancer−induced bone metastases, a complex biological and therapeutic target. Curr Mol Biol Rep. 2018;4:123–31.

Article  Google Scholar 

Tran MT. Metastatic breast cancer-derived exosomes and osteoclast-mediated bone metastasis. J Breast Cancer Res. 2023;3:8–10.

Article  Google Scholar 

Gu P, Sun M, Li L, Yang Y, Jiang Z, Ge Y, et al. Breast tumor-derived exosomal MicroRNA-200b-3p promotes specific organ metastasis through regulating CCL2 expression in lung epithelial cells. Front Cell Dev Biol. 2021;9: 657158.

Article  PubMed  PubMed Central  Google Scholar 

Ono M, Kosaka N, Tominaga N, Yoshioka Y, Takeshita F, Takahashi R, et al. Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells. Sci Signal. 2014;7(332):ra63–ra63.

Article  PubMed  Google Scholar 

Yokoi A, Yoshioka Y, Yamamoto Y, Ishikawa M, Ikeda S, Kato T, et al. Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer. Nat Commun. 2017;8:14470.

Article  PubMed  PubMed Central  Google Scholar 

Zhang T, Zhou H, Wang K, Wang X, Wang M, Zhao W, et al. Role, molecular mechanism and the potential target of breast cancer stem cells in breast cancer development. Biomed Pharmacother. 2022;147: 112616.

Article  CAS  PubMed  Google Scholar 

Li B, Lu Y, Yu L, Han X, Wang H, Mao J, et al. miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation. Chem Biol Interact. 2021;25(354): 109556.

Article  Google Scholar 

Song SJ, Poliseno L, Song MS, Ala U, Webster K, Ng C, et al. MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. Cell. 2013;154(2):311–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell. 2012;148:1015–28.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wolfson B, Eades G, Zhou Q. Roles of microRNA-140 in stem cell-associated early stage breast cancer. World J Stem Cell. 2014;6(5):591–7.

Article  Google Scholar 

Hemler ME. Tetraspanin functions and associated microdomains. Nat Rev Mol Cell Biol. 2005;6:801–11.

Article  CAS  PubMed  Google Scholar 

Detchokul S, Williams ED, Parker MW, Frauman AG. Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies. Br J Pharmacol. 2013;171:5462–90.

Article  Google Scholar 

Galindo-Hernandez O, Villegas-Comonfort S, Candanedo F, González-Vázquez M-C, Chavez-Ocaña S, et al. Elevated concentration of microvesicles isolated from peripheral blood in breast cancer patients. Arch Med Res. 2013;44:208–14.

Article  CAS  PubMed  Google Scholar 

Wang X, Zhong W, Bu J, Li Y, Li R, Nie R, et al. Exosomal protein CD82 as a diagnostic biomarker for precision medicine for breast cancer. Mol Carcinog. 2019;58:674–85.

Article  CAS  PubMed  Google Scholar 

Rupp A-K, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, et al. Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage. Gynecol Oncol. 2011;122:437–46.

Article  CAS  PubMed  Google Scholar 

Ciravolo V, Huber V, Ghedini GC, Venturelli E, Bianchi F, Campiglio M, et al. Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy. J Cell Physiol. 2011;227:658–67.

Article  Google Scholar 

Kibria G, Ramos EK, Lee KE, Bedoyan S, Huang S, Samaeekia R, et al. A rapid, automated surface protein profiling of single circulating exosomes in human blood. Sci Rep. 2016;6:36502.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Comments (0)

No login
gif