Lal A. Iron in health and disease: an update. Indian J Pediatr. 2020;87(1):58–65.
Testa U. Recent developments in the understanding of iron metabolism. Hematol J. 2002;3(2):63–89.
Article CAS PubMed Google Scholar
Abbaspour N, Hurrell R, Kelishadi R. Review on iron and its importance for human health. J Res Med Sci. 2014;19(2):164.
PubMed PubMed Central Google Scholar
Cerami C. Iron nutriture of the fetus, neonate, infant, and child. Ann Nutr Metab. 2017;71(Suppl. 3):8–14.
Article CAS PubMed Google Scholar
Rukuni R, Knight M, Murphy MF, Roberts D, Stanworth SJ. Screening for iron deficiency and iron deficiency anaemia in pregnancy: a structured review and gap analysis against UK national screening criteria. BMC Pregnancy Childbirth. 2015;15(1):1–11.
Pavord S, Myers B, Robinson S, Allard S, Strong J, Oppenheimer C, et al. UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol. 2012;156(5):588–600.
Article CAS PubMed Google Scholar
Ross A, Caballero B, Cousins R, Tucker K, Ziegler T, Katherine Camacho Carr C. Modern nutrition in health and disease (Modern Nutrition in Health & Disease (Shils)). Copy Right Lippincott Williams Wilkins. 2012:248-70.
Krebs NF, Lozoff B, Georgieff MK. Neurodevelopment: the impact of nutrition and inflammation during infancy in low-resource settings. Pediatrics. 2017;139(Supplement 1):S50–S8.
Bastin J, Drakesmith H, Rees M, Sargent I, Townsend A. Localisation of proteins of iron metabolism in the human placenta and liver. Br J Haematol. 2006;134(5):532–43.
Article CAS PubMed Google Scholar
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 2000;403(6771):776–81.
Article ADS CAS PubMed Google Scholar
Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 2005;1(3):191–200.
Article CAS PubMed Google Scholar
Muckenthaler MU, Galy B, Hentze MW. Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annu Rev Nutr. 2008;28:197–213.
Article CAS PubMed Google Scholar
Kühn LC. Iron regulatory proteins and their role in controlling iron metabolism. Metallomics. 2015;7(2):232–43.
Sangkhae V, Fisher AL, Wong S, Koenig MD, Tussing-Humphreys L, Chu A, et al. Effects of maternal iron status on placental and fetal iron homeostasis. J Clin Investig. 2021;130(2).
Wang Y, Wu Y, Li T, Wang X, Zhu C. Iron metabolism and brain development in premature infants. Front Physiol. 2019;10:463.
Article PubMed PubMed Central Google Scholar
Simpson IA, Ponnuru P, Klinger ME, Myers RL, Devraj K, Coe CL, et al. A novel model for brain iron uptake: introducing the concept of regulation. J Cereb Blood Flow Metab. 2015;35(1):48–57.
Article CAS PubMed Google Scholar
Ferreira A, Neves P, Gozzelino R. Multilevel impacts of Iron in the brain: the cross talk between neurophysiological mechanisms, cognition, and social behavior. Pharmaceuticals. 2019;12(3):126.
Article CAS PubMed PubMed Central Google Scholar
Bezerra CT, Grande AJ, Galvão VK, Santos DHMd, Atallah ÁN, Silva V. Assessment of the strength of recommendation and quality of evidence: GRADE checklist. A descriptive study. Sao Paulo Med J. 2022;140:829–36.
PubMed PubMed Central Google Scholar
Magrin GL, Strauss FJ, Benfatti CAM, Maia LC, Gruber R. Effects of short-chain fatty acids on human oral epithelial cells and the potential impact on periodontal disease: a systematic review of in vitro studies. Int J Mol Sci. 2020;21(14):4895.
Article CAS PubMed PubMed Central Google Scholar
Findlay E, Ng KT, Reid RL, Armstrong SM. The effect of iron deficiency during development on passive avoidance learning in the adult rat. Physiol Behav. 1981;27(6):1089–96.
Article CAS PubMed Google Scholar
Eseh R, Zimmerberg B. Age-dependent effects of gestational and lactational iron deficiency on anxiety behavior in rats. Behav Brain Res. 2005;164(2):214–21.
Article CAS PubMed Google Scholar
Jougleux J-L, Rioux FM, Church MW, Fiset S, Jacques H, Surette ME. Dietary LC-PUFA in iron-deficient anaemic pregnant and lactating guinea pigs induce minor defects in the offsprings’ auditory brainstem responses. Nutr Neurosci. 2016;19(10):447–60.
Article CAS PubMed Google Scholar
Boksa P, Zhang Y, Nouel D, Wong A, Wong TP. Early development of Parvalbumin-, somatostatin-, and cholecystokinin-expressing neurons in rat brain following prenatal immune activation and maternal Iron deficiency. Dev Neurosci. 2016;38(5):342–53.
Article CAS PubMed Google Scholar
Vieyra-Reyes P, Millán-Aldaco D, Palomero-Rivero M, Jiménez-Garcés C, Hernández-González M, Caballero-Villarraso J. An iron-deficient diet during development induces oxidative stress in relation to age and gender in Wistar rats. J Physiol Biochem. 2017;73(1):99–110.
Article CAS PubMed Google Scholar
Moos T, Skjørringe T, Thomsen LL. Iron deficiency and iron treatment in the fetal developing brain–a pilot study introducing an experimental rat model. Reprod Health. 2018;15(1):117–20.
Rees WD, Hay SM, Hayes HE, Stevens VJ, Gambling L, McArdle HJ. Iron deficiency during pregnancy and lactation modifies the fatty acid composition of the brain of neonatal rats. J Dev Orig Health Dis. 2020;11(3):264–72.
Article CAS PubMed Google Scholar
Hsieh H-Y, Chen Y-C, Hsu M-H, Yu H-R, Su C-H, Tain Y-L, et al. Maternal iron deficiency programs offspring cognition and its relationship with gastrointestinal microbiota and metabolites. Int J Environ Res Public Health. 2020;17(17):6070.
Article CAS PubMed PubMed Central Google Scholar
Amin SB, Orlando M, Wang H. Latent iron deficiency in utero is associated with abnormal auditory neural myelination in≥ 35 weeks gestational age infants. J Pediatr. 2013;163(5):1267–71.
Article CAS PubMed Google Scholar
Wang J, Wang H, Chang S, Zhao L, Fu P, Yu W, et al. The influence of malnutrition and micronutrient status on anemic risk in children under 3 years old in poor areas in China. PloS one. 2015;10(10):e0140840.
Article PubMed PubMed Central Google Scholar
Berglund SK, Torres-Espínola FJ, García-Valdés L, Segura MT, Martínez-Zaldívar C, et al. The impacts of maternal iron deficiency and being overweight during pregnancy on neurodevelopment of the offspring. Br J Nutr. 2017;118(7):533–40.
Article CAS PubMed Google Scholar
Prado EL, Sebayang SK, Apriatni M, Adawiyah SR, Hidayati N, Islamiyah A, et al. Maternal multiple micronutrient supplementation and other biomedical and socioenvironmental influences on children’s cognition at age 9–12 years in Indonesia: follow-up of the SUMMIT randomised trial. Lancet Glob Health. 2017;5(2):e217–e28.
Wainstock T, Walfisch A, Sergienko R, Sheiner E. Maternal anemia and pediatric neurological morbidity in the offspring–Results from a population based cohort study. Early Hum Dev. 2019;128:15–20.
Riahi SM, Mohammadi M, Fakhri Y, Pordanjani SR, Soleimani F, Saadati HM. Prevalence and determinant factors of anemia in children aged 6–12 months after starting an iron supplement in the east of Iran. Arch de Pediatr. 2019;26(6):347–51.
Tenorio-Laranga J, Männistö PT, Karayiorgou M, Gogos JA, García-Horsman JA. Sex-dependent compensated oxidative stress in the mouse liver upon deletion of catechol O-methyltransferase. Biochem Pharmacol. 2009;77(9):1541–52.
Article CAS PubMed Google Scholar
Bae S, Zhang L. Gender differences in cardioprotection against ischemia/reperfusion injury in adult rat hearts: focus on Akt and protein kinase C signaling. J Pharmacol Exp Ther. 2005;315(3):1125–35.
Article CAS PubMed Google Scholar
Jackson RT, Hamad NA, Al-Somaie M, Guoad NA, Prakash P. Gender and age differences in anemia prevalence during the lifecycle in Kuwait. Ecol Food Nutr. 2004;43(1-2):61–75.
Antunes H, Santos C, Carvalho S, Gonçalves S, Costa-Pereira A. Male gender is an important clinical risk factor for iron deficiency in healthy infants. e-SPEN J. 2012;7(6):e219–e22.
Felt BT, Beard JL, Schallert T, Shao J, Aldridge JW, Connor JR, et al. Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behav Brain Res. 2006;171(2):261–70.
Article CAS PubMed PubMed Central Google Scholar
Algarín C, Peirano P, Garrido M, Pizarro F, Lozoff B. Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning. Pediatr Res. 2003;53(2):217–23.
Comments (0)